On the new patch, this weekend's MDI Cup will likely feature some key differences from the previous ones. On the class-balance front, some top performing MDI specs like Vengeance, Marksmanship, Windwalker have seen nerfs - my suspicion is that Vengeance will continue to dominate but Windwalker and Marksmanship will see a diminished role. Other specs that were already doing well in the MDI have seen some buffs, such as Night Fae Priests!
Necrolords have largely been absent from the MDI, save in Theater of Pain
and sometimes Plaguefall
due to their covenant synergies in those dungeons. The re-work to the Fleshcraft
ability certainly will enhance their standing on the live servers, but in a speedrun environment it's less likely to bring the covenant over the line for any specs.
In specific dungeons, some strategies may be adjusted. For instance, the Master Assassin
legendary power that Rogues used to great effect in The Necrotic Wake
has been changed to no longer function in that way. This may lead to a re-imagining of Necrotic Wake away from the massive pulls facilitated by double damage weapons wielded by Rogues, or it may just require those pulls to be executed even better as they'll live for longer.